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Raw Flibanserin paʻu (167933-07-5)

O le paʻu Flibanserin le paʻu o se vailaau faʻasaina ua faʻamaonia mo le togafitiga o fafine o le vaʻavaʻavaʻa ma mauaina, faʻatautaia masani feusuaiga masani ....


Tulaga: I le Gaosiga o Gaosiga
Vaega: 25kg / Drum
tulaga: 1489kg / masina

faʻamatalaga

Fulu o le Flibanserin powder (167933-07-5)

Raw Flibanserin paʻu (167933-07-5)

Laʻi Flibanserin paʻu, faʻatau atu i lalo o le igoa tau fefaʻatauaʻiga Addyi, o le agonist serotonin multifunctionin and antagonist lea e faʻaaogaina mo le togafitiga o tamaitai o le muaʻi moaopausal e iai le maʻi tuʻinanau o le manaʻoga faʻafeusuaiga (HSDD). O le vailaʻau e faʻateleina ai le numera o mea tau feusuaʻiga faamalieloto i le masina e tusa ma le tasi le afa i luga o le placebo mai se amataga o le lua i le tolu. I le taimi lava e tasi, O loʻo i ai se matafaioi o se faʻamaʻi serotoneric, o se seronoterical attack and a antidepressant ..

Raw Flibanserin paʻu (167933-07-5) Sfaʻamatalaga

Igoa oloa Raw Flibanserin paʻu
Suafa Suafa 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
faʻailogaina Nma Faʻaopoopo
Vailaʻau Vailaʻau Mulinuu le serotonin agonist ma le tagata tetee
Numera CAS 167933-07-5
InChIKey PPRRDFIXUUSXRA-UHFFFAOYSA-N
Molecular Famulamu C20H21F3N4O
Molecular Wvalu 390.41 g / mol
Masima Monoisotopic 390.167 g / mol
Fufulu Pmanogi 225 ° C
Lapoʻa Mata N / A
Half-Life Biological ~ 11 itula
lanu Paʻepaʻe i le beige
Sfaʻamalosia DMSO: soluble10mg / mL, manino
Storage Tsuauu 2-8 ° C
Raw Flibanserin paʻu Afaʻasologa Atiae mo le togafitiga o le manaʻoga faʻafeusuaiga faʻaleagaina e le lelei i tamaitai

Raw Flibanserin paʻu (167933-07-5) Faʻamatalaga

Flibanserin pefu o le uluai vailaau faʻasaina e tatau ona faʻamaonia mo le faʻamausaligia o le manaʻoga faʻafeusuaʻiga mama (HSDD) i fafine o le vaʻavaʻavavave e le FDA i Aokuso 2015. O le amataga na fausia e le Boehringer Ingelheim, o se vailaau faʻasaina, ae na faʻaalia ai le leai o se aoga i faigata ma na faʻalauteleina e avea ma faʻamaʻi pipisi o le faʻafitauli o feusuaʻiga e le Sprout Pharmaceuticals. Flibanserin's mechanism of action is attributed to its highity affinity for 5-HTA1 and 5-HTA2 receptors, e faaalia ai le agonist activity on 5-HTA1 and antagonist on 5-HTA2, e mafua ai le faaitiitia o le serotonin i totonu o le mafaufau faapea foi ma le aafiaga i le faateleina o norepinephrine ma le dopamine neurotransmitters.

Flibanserin paʻu (167933-07-5) Faʻamaumauga o le Faʻatino

Flibanserin's mechanism of action is attributed to its highity affinity for 5-HTA1 and 5-HTA2 receptors, e faaalia ai le agonist activity on 5-HTA1 and antagonist on 5-HTA2, e mafua ai le faaitiitia o le serotonin i le mafaufau ma faapea foi ona i ai le aafiaga i le faateleina o norepinephrine ma le dopamine neurotransmitters. Flibansetrin e maualuga lona mafanafana mo serotonin receptors i le faiʻai: o loʻo galue o se tagata ola i luga o le 5-HT1A ma se tagata faʻatau i le 5-HT2A. I vivo, flibanserin e fusifusia tutusa i le 5-HT1A ma 5-HT2A receptors. Ae peitai, i lalo o maualuga maualuga o le faiʻai 5-HT (ie, i lalo o le atuatuvalega), flibanserin atonu e aofia ai le senituri 5-HT2A i le maualuga atu nai lo le 5-HT (1A). E mafai foʻi ona faʻafefeteina faʻamaoni D4 (dopamine) ma le 5-HT2B ma le 5-HTB2C. O ana gaioiga i le neurotransmitters receptors e mafai ona fesoasoani i le faʻaitiitia o tulaga o le serotonin ma faateleina le dopamine ma norepinephrine, o mea uma e mafai ona faia se vaega i le taulimaina o taui. Flibanserin ua faatauina atu i lalo ole igoa tau fefaatauaiga Addyi ma ua faailoa mai mo le togafitiga o tamaitai o le vaʻavaʻavaʻa ma le mauaina o le faʻasolosolo o le gasegase o le manaʻoga faʻafeusuaiga (HSDD) e pei ona faʻailoaina i le maualalo o manaoga faʻafeusuaiga lea e mafua ai le le mautonu poʻo le faigata faʻapitoa.

Faʻaaogāina o le paʻu Flibanserin (167933-07-5)

Flibanserin le paʻu o le 5-HT1A agonist ma le 5-HT2A faʻataʻitaʻiga lea na atiaʻe mo le togafitia o le manaʻoga faʻafeusuaʻiga mama i fafine (1,2).

Fautuaina Flubanserin paʻu (167933-07-5) Faʻailoga

100 mg faʻamalo tasi i le aso i le taimi e momoe ai

Umi o le togafitiga: O lenei vailaʻau e tatau ona faamutaina pe a mavae le 8 vaiaso pe afai e le lipotia e le tagata maʻi se faʻaleleia atili o uiga.

Faʻamatalaga: O lenei vailaʻau e le o faʻaalia e faʻaleleia atili ai feusuaiga, ma e leʻo faʻamatalaina mo togafitiga i fafine pe a maeʻa ona maliliu.

O aʻafiaga o le paʻu Flibanserin (167933-07-5)

O mea mataga e sili ona taatele i le va o fafine o loʻo uuina le flibanserin paʻu. O le tele o mea leaga na tutupu na agavaʻa tele. O mea e sili ona lauiloa na lipotia mai e aofia ai le vevela, gaioiga, lagona lelava, moe, ma faafitauli moe.

O le inuina o le ava ao iai i le flibanserin pauu e mafai ona mafua ai le maualalo o le toto maualuga (maualalo le toto maualuga lea na maua ai faailoga i le maea ai o le 2 tioata uaina i 17%).

FAUFUAGA MA TALANOA:

O lenei Mea ua Faʻaaoga Mo Suesuega Faʻaaoga Naʻo. Faʻamaumauga o le Faʻatauga. E le mo le Faʻatauga a le Tagata, poʻo le Fomaʻi, Vailaʻau Vaʻaia, poʻo le Aiga.


Shangke Chemicals o se atinaʻe tekonolosi e faʻapitoa i vailaau faʻatautaia o vailaau mo togafitiga (API). Mo le pulea o le tulaga lelei i le gasologa o le gaosiga, o se numera tele o polofesa poto faapitoa, o meafaigaluega gaosi muamua ma fale suesue ua avea ma autu autu.

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