NADH 2Na (606-68-8)

Mati 15, 2020

O le NADH o se ituaiga o le nikotinamide adenine dinucleotide (NAD) o le enzyme, o se sela galue malosi o se vaega ma vailaʻau B3 ……….

 


Tulaga: I le Gaosiga o Gaosiga
Tuʻuina ma Faʻasalalau Faʻapitoa
tulaga: 1277kg / masina

NADH 2Na (606-68-8) vitio

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) Faʻamatalaga

Igoa oloa Beta-Nicotinamide adenine dinucleotide disodium masima (NADH 2Na)
Suafa Suafa NADH (disodium salt); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium Salt; Nicotinamide adenine dinucleotide, faaitiitia;
Numera CAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILE C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Faiga Faʻavae Molecular C21H27N7Na2O14P2
Taumaʻa Masele 709.4
Masima Monoisotopic 709.088661 g / mol
Melting Point 140-142 ℃
lanu Lanu samasama
Stora temp 2-8 ℃
Solubility H2O: 50 mg / mL, manino i toetoe lava manino, samasama
talosaga Fomaʻi; taumafa ma mea taumafa;

 

O le a le Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)?

NADH o se ituaiga o nikotinamide adenine dinucleotide (NAD) enzyme, o se gaioiga coenzyme ituaiga o se tuufaatasiga ma vitamini B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Sate, faʻaititia, ua lauiloa foi o le Nicotinamide adenine dinucleotide, o se coenzyme i redox tali. O ana gaioiga o se toefaʻaleleia o le eletise foaʻi i catabolic gaioiga e aofia ai glycolysis, ox-oxidation ma le citric acid taʻamilosaga (Krebs taʻamilosaga, TCA taʻamilosaga). NADH disodium masima o loʻo auai foi i sela faailoina gaioiga, mo se faʻataʻitaʻiga o se substrate mo le poly (ADP-ribose) polymerases (PARPs) i le taimi o le DNA faʻaleagaina tali. I le avea ai o le disodium masima o le NADH, e faʻaaogaina i meaʻai ma mea paleni faʻaopopo i le togafitia o le faʻamaʻi o Parkinson, maʻi o le vaivai o le tino, faʻamaʻi o le Alzheimer ma faʻamaʻi fatu.

 

Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) manuia

I le avea ai o se coenzyme o oxidoreductases, NADH disodium masima e taua tele i le malosi o le tino.

- NADH disodium masima e ono taitai atu ai i le sili atu manino manino, mataala, mafaufau loloto, ma manatua. E ono faʻateleina ai le mafaufau ma ono faʻateleina ai lagona. E mafai ona faʻateleina le malosi i le tino ma faʻamalosia le metabolism, faiʻai le malosi ma le tumau.

- Fesoasoani i tagata e maua ile faʻalavelave ile mafaufau, toto maualuga pe maualuga le suka;

- Faʻaleleia le taʻaloga afeleti;

- Tolo le tuai faʻagasologa ma faʻatumauina le faʻamaoni o neula sela e lagolago ai le neula;

- E mafai ona togafitia faʻamaʻi Parkinson, faʻaleleia le gaioiga o neurotransmitters i le faiʻai o tagata mamaʻi ma le faʻamaʻi Parkinson, faʻaititia le faʻaletino tino ma manaʻoga vailaʻau;

- Togafitiga faʻafitauli vaivai masani (CFS), faʻamaʻi o le Alzheimer ma faʻamaʻi fatu;

- Puipui mai i aafiaga o le vailaʻau o le AIDS ua taʻua o le zidovudine (AZT);

- Tetee aʻafiaga a le 'ava malosi i le ate;

- Lelava

 

Beta-Nicotinamide adenine dinucleotide disodium masima (NADH 2Na) itu aʻafiaga:

I le taimi nei, o le NADH disodium masima e foliga mai e saogalemu mo le tele o tagata pe a faʻaaoga tatau ma le pupuu, e oʻo atu i le 12 vaiaso. O le toʻatele o tagata e leai ni aʻafiaga i le taimi e ave ai le mea fautuaina i aso taitasi, e 10 mg.

Ae peitai, e le lava le tala e uiga i le faaaogaina o le NADH disodium salt i le taimi o le maʻitaga ma le fafagaina o susu, o lea e tatau ai ona latou nofo i le itu saogalemu ma aloese mai le faʻaaoga.

 

Tusitaiala o le:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - o se togafitiga fou i le faʻamaʻi a Parkinson. Faʻatusatusaga o le tautala ma le matua talosaga. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. O le Merck Index. 12th lomiga. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O le faʻaʻotoʻese faʻaititia o le B-nicotinamide adenine dinucleotide (NADH) e aʻafia ai le toto, le lipid peroxyidation, ma le lipid profile i rats hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. O le faʻaʻotoʻese faʻaititia o le B-nicotinamide adenine dinucleotide (NADH) e aʻafia ai le toto, le lipid peroxyidation, ma le lipid profile i rats hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. O le coenzyme Q10 faatasi ai ma le NADH faaopoopo e faʻaleleia atili le vaivai ma mea faʻasolosolo ile mea ole gasegase tumau ole maʻi? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Togafitiga o le faʻamaʻi o Parkinson ma le NADH. Acta Neurol Scand 1994; 90: 345-7.