NADP disodium masima (24292-60-2)

NADP disodium masima (24292-60-2) vitio

β-Nicotinamide adenine dinucleotide phosphate disodium salt (NADP disodium masima) Sfaʻamatalaga

O le a le β-Nicotinamide adenine dinucleotide phosphate disodium salt (NADP disodium salt)?

Nicotinamide adenine dinucleotide phosphate (NADP +) o se cofactor faʻaaogaina i anabolic tali. β-Nicotinamide adenine dinucleotide phosphate disodium salt o se disodium salt o le NADP +, o se coenzyme talafeagai mo le faʻamalosia o le ava malosi o le kulukose ma le faʻamagoina o le oxidative o isi vailaʻau. Ma e tupu lautele i ola vaega, aemaise lava i le ate.

O le Nicotinamide adenine dinucleotide phosphate (NADP) ma le NADPH o loʻo faia ai se paaga toe faʻaleleia. Le fuainumera NADPH / NADP e faʻatonutonu ai le malosi o le intracellular redox, aemaise lava le tali anaerobic, ma aʻafia ai le tali o le metabolic i le tino. O faʻataʻitaʻiga o le lipid ma le nucleic acid synthesis. O le NADP o se paʻu o le coenzyme i ituaiga cytochrome P450 ma oxidase / reductase faʻataʻitaʻiga e pei o le thioredoxin reductase / thioredoxin system.

O le NADPH o loʻo tuʻuina atu ai le faʻaitiʻitia o mea tutusa mo le gaosiga o le biosynthetic ma maua ai aʻafiaga e puipuia ai le faʻaleagaina o meaola o le okesene faʻamalosia (ROS), ma faʻafouina ai le faʻaaogaina o le kulutathione (GSH). E faʻaaogaina foi i ala faʻapitoa e pei o le cholesterol synthesis ma le faʻamalosia o le suauu.

E le gata i lea, o le NADPH o loʻo aʻafia foi mo le fatuina o aʻafiaga saoloto i totonu o siama puipuia i NADPH oxidase. O nei faʻamalosi saoloto e faʻaaogaina e faʻaleagaina ai faʻamaʻi i se gaioiga e pei o le manava o le tino. O le faʻaititia o le tutusa o le cytochrome P450 hydroxylated aromatics, steroids, ava malosi, ma vailaʻau.

talosaga o le β-Nicotinamide adenine dinucleotide phosphate disodium salt

O le Nicotinamide adenine dinucleotide phosphate (NADP) ma le NADPH o loʻo faia ai se paaga toe faʻaleleia. O le NADP / NADPH o se coenzyme e lagolagoina ai le toe faʻafoʻiina o mea eleelea e ala i le felauaiga o electrons i le tele o faʻaoga, aemaise lava faʻasolosolo anaerobic e pei o le lipid ma le nucleic acid synthesis. NADP / NADPH o se ulugalii coenzyme i ituaiga cytochrome P450 ma oxidase / reductase polokalama faʻafoe, e pei o le thioredoxin reductase / thioredoxin system.

O isi enzymes o loʻo faʻaaogaina le NADP o se coenzyme o: Alcohol dehydrogenase: NADP faʻatuatuaina; AOLA ADH: NADP faʻatuatuaina; Ferredoxin-NADP faʻataʻitaʻiga; L-Fucose dehydrogenase; Gabase; Galactose-1-phosphate uridyl transferase; Glucose dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase: NADP patino; Isocitric dehydrogenase; Maliki enzymes; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase ma Succinic semialdehyde dehydrogenase.

Tusitaiala o le:

• Hashida SN, Kawai-Yamada M. Inter-Organelle NAD Metabolism Faʻamautuina le Malamalama Tali NADP Dynamics i Laʻau. Faʻasologa o Suga Sci. 2019 Iul. 26; 10: 960. doi: 10.3389 / fpls.2019.00960. eCollection 2019. PMID: 31404160. PMCID: PMC6676473.
• O le tuberculosis o le NCC + ma le NADP + glycohydrolase o loʻo i ai ma le elemene o meatotino .J Biol Chem. 2019 Mati 1; 294 (9): 3024-3036. Nuʻu: 10.1074 / jbc.RA118.005832. Epub 2018 Tesema 28. PMID: 30593509. PMCID: PMC6398120.
• Liang J, Huang H, Wang S. Distribution, Evolution, Malosiaga Faʻatekonolosi, ma Galuega Faʻatekinolosi o le Faʻatekonolosi-Faʻamaufaʻatasia e le Flavin-NADH-Dependent Faʻaitiiti Ferredoxin: NADP + Oxidoreductase. Front Microbiol. 2019 Mati 1; 10: 373. doi: 10.3389 / fmicb.2019.00373. eCollection 2019. PMID: 30881354. PMCID: PMC6405883.
• Kawai S, Murata K. "Faʻatulagaina ma gaioiga o le NAD kinase ma le NADP phosphatase: o enzymes autu e faʻatonutonuina le paleni o le NAD (H) ma le NADP (H)". Bioscience, Biotechnology, ma le Biochemistry. 72 (4): 919–30. faia: 10.1271 / bbb.70738. PMID 18391451.
• Hanukoglu I. "Faʻasao o le Enzyme-Coenzyme Interfaces i le FAD ma le NADP Binding Adrenodoxin Reductase-A Ubiquitous Enzyme". Tusi o tala o le Molecular Evolution. 85 (5–6): 205–218. Tusi faʻamau: 2017JMolE..85..205H. faia: 10.1007 / s00239-017-9821-9.PMID 29177972.